Updated 8/31/23. The SugaREX nutraceutical by the Diverxin company has been called “the organic way to support healthy blood sugar levels” and the glucose support formula “your doctor never told you about.” Those are pretty bold claims, but is this oral supplement really a legit diabetes solution? Let's look at the ingredients in SugaREX, their pros and cons, the side effects, safety info, and what I liked and didn't like about it.
What Are The Health Benefits of Diverxin SugaREX?
This supplement is said to:
- help you achieve healthy blood sugar numbers
- increase the sensitivity of insulin and leptin
- improve blood circulation
- reduce fatigue and boost overall energy levels
Of course, keep in mind SugaREX (also pronounced SugarEX) has not been clinically investigated by doctors to know for sure if it does any of these things. That said, based on the ingredients, SugaREX appears to be primarily a blood sugar support supplement. Obviously, high blood sugar levels are linked to diabetes and prediabetes (metabolic syndrome/ syndrome X) but equally concerning, diabetes appears to accelerate the aging process. More people die -sooner than normal- from the complications of diabetes than from the disease itself. For example, unchecked diabetes is linked to:
- Heart disease (the #1 killer of Americans)
- High blood pressure
- Stroke (the #4 killer)
- Kidney disease/kidney failure
- Diabetic neuropathy – which also raises the risk of falling and injuring yourself
So maintaining an optimal level – not too high and not too low – of blood sugar is an important part of diabetes management.
By some estimates, 25% of modern medicines are derived from plants – and only 5% to 15% of total plants on Earth have been studied for their medicinal benefits. The SugaREX formula contains several vitamins, minerals, and plant-derived compounds, which various studies appear to show improve blood sugar levels.
SugaREX or SugarEX?
Some may choose to pronounce the name SugarEX since sugar is an actual word and may make more sense for some. The spelling of both words is identical except where the emphasis is placed. Why does the Diverxin company spell it SugaREX? It's a play on words? Since “RX” is the abbreviation for a prescription, spelling it this way gives one the idea that the supplement is the prescription for high blood sugar levels. Obviously, we are discussing a supplement here and not a prescription medication.
What Are The Ingredients in Diverxin SugaREX Formula?
|Amount||Percent Daily Value|
|Vitamin C (ascorbic acid)||50 mg||83%|
|Vitamin E (d-alpha tocopheryl acetate)||15 IU (10 mg)||50%|
|Magnesium oxide||7.5 mg||50%|
|Banaba leaf||25 mg||N/A|
|Bitter melon||50 mg||N/A|
|Licorice root extract||50 mg||N/A|
|Cinnamon bark powder||50 mg||N/A|
|Gymnema sylvestre leaf powder||50 mg||N/A|
|Yarrow flowers powder||50 mg||N/A|
|Cayenne pepper powder||10 mg||N/A|
|Juniper berry powder||25 mg||N/A|
|White mulberry leaf powder||25 mg||N/A|
|Vanadium (vanadyl sulfate)||200 mcg||N/A|
|Alpha lipoic acid||30 mg||N/A|
N/A = no dietary allowance has been established.
The supplement also contains vegetable cellulose and rice bran as inactive ingredients.
How Do You Take Deverxin SugaREX? Directions For Using
The company recommends taking one capsule twice a day, preferably 20 to 30 minutes before a meal, with 8 oz of water. If you follow the guidelines, a bottle will last you one month. The company does not specify if it's best to take SugaREX with breakfast, lunch, or at dinner time. In theory, if it really works, it may make sense to take it before breakfast and before dinner so that the nutrients stay in your system the longest. This is speculation on the part of this reporter.
Vitamin C (Ascorbic Acid) 50 mg
Vitamin C is a water-soluble micronutrient that is not made by humans. Thus, it's important to consume it regularly. While scurvy is a classic vitamin C deficiency syndrome, it only takes about 10 mg a day to prevent this disease. The RDA for vitamin C is 90 mg daily for men and 70 mg daily for women.
Some research hints that vitamin C supplementation may lower fasting blood sugar levels and may be particularly effective in older adults.
Vitamin E (D-Alpha Tocopherol) 15 IU
Vitamin E is a well-known antioxidant that can reduce the harmful effects of free radicals. Why it's in a diabetes supplement like this one likely stems from evidence linking high blood sugar levels to an increase in free radical production and thoughts it may have beneficial effects on blood vessel function. In addition, researchers, in one study, reported vitamin E supplements reduced post-prandial blood sugar levels (blood sugar after eating), diastolic blood pressure (the bottom number), and total cholesterol levels in people who had either type I or type II diabetes.
SugaREX makers provide 15 IU (10 mg) in each capsule, which is 50% of the daily value of this fat-soluble vitamin. Vitamin E comes in two forms a D and an L form. The D form is considered more active, so SugaREX provides D-alpha tocopherol.
Biotin (Vitamin B7) 300 mcg
Also, sometimes called “vitamin H,” biotin is mostly associated with hair, skin, and nail supplements. However, biotin also activates genes that lower blood sugar. Deficiencies in this nutrient have been linked to impaired glucose tolerance – which can result in elevated blood sugar levels. Smoking can also reduce biotin levels. Each capsule of SugaREX provides 100% of the recommended daily allowance of this nutrient, which ensures deficiencies, however unlikely, do not occur.
Watch this video to see more about how biotin helps diabetes.
Magnesium (7.5 mg)
The mineral magnesium is crucial for over 300 biochemical reactions in the human body. We even need magnesium to make cellular energy. The recommended dietary allowance for this nutrient is 400 to 420 mg per day for men and 310 to 320 mg for women. Given its importance, it's unfortunate many do not consume enough magnesium, which may lead to sub-clinical deficiency. Some reports show raising magnesium levels may help depression. Magnesium is well known to reduce fasting blood sugar levels in people with diabetes and those who are at risk of getting diabetes.
Each capsule of Deverxin SugaREX provides 50% of the daily value for this mineral, which can help ensure deficiencies don't occur, especially if combined with eating foods that contain magnesium. Generally, green foods and foods with fiber contain magnesium. SugaREX contains magnesium oxide, which will raise magnesium levels but may be less absorbable than other forms, such as this full spectrum supplement I experimented with and liked.
Manganese 1 mg
Manganese is a trace mineral. Restricting manganese in animals usually impairs how well their insulin functions, although studies in people are somewhat conflicting. In one study that followed people for 5 years, those who consumed more manganese had lower levels of developing type II diabetes.
Each capsule of SugaREX contains 1 mg, which may not sound like much until you understand this is 50% of the recommended daily intake. Adequate amounts of dietary manganese are thought to range from 1.8 to 2.3 mg per day for adult women and men, respectively (less for children). Remember, manganese is a trace mineral so we don't need much of it. Vegans tend to have higher levels of manganese than meat eaters. This is because plant foods tend to be high in this nutrient. Food sources include green leafy vegetables, beans, whole grain foods, and tea. Pecans have some of the highest manganese levels, with 1 oz containing over 1 mg.
Diverxin, the manufacturer of the SugaREX supplement, uses a chelated form of manganese (amino acid chelate), which significantly increases the absorption of this mineral.
Banaba leaf (Lagerstroemia speciosa) 25 mg
Reports of Banaba helping diabetes date back to at least 1940. Corosolic acid is the extract in banaba thought to be responsible for its blood sugar-lowering effects. Some research suggests that corosolic acid banaba leaf extract supplements begin reducing blood sugar levels within 60 minutes of consumption. Equally interesting is that it does not appear to cause hypoglycemia either. That said, it's possible the whole leaf contains several extracts that may work synergistically to improve blood sugar control.
Guggul (Commiphora mukul) 50 mg
Guggul, also known as Oleogum resin, is derived from the bark of the guggul tree (Commiphora mukul), native to India has been used in ayurvedic medicine to mitigate a number of health concerns ranging from acne to abnormal cholesterol levels. Other names for this ancient medicine are guggulipid and Indian Myrrh. Those familiar with the Book of Mathew of the Bible know that gold, frankincense, and myrrh were presents given to the baby Jesus by the three wise men.
While human research demonstrating its effectiveness for lowering blood sugar is lacking, studies do show guggle may lower cholesterol and bad LDL cholesterol levels by about 10% and 20%. Other research suggests guggulipids may reduce inflammation, which might explain some of its heart-healthy effects.
One of the claims for SugaREX is that it may help support healthy weight loss. Animal research suggests guggulsterones might suppress appetite. This needs to be confirmed in humans, though.
Guggle & Weight Loss
Bitter Melon (Momordica charantia) 50 mg
Bitter melon, also called karela, and balsam pear grows in India and Asia and is called such because of the bitter taste of the fruit. The fruit looks like an ugly cucumber and contains many nutrients such as potassium, fiber, magnesium, folate, vitamin C, B1 (thiamin), B2 (riboflavin), B3 (niacin), and zinc. The extracts in bitter melon thought to be responsible for its anti-diabetes effects are triterpenes and various phenol-like compounds. In spite of its popularity, clinical studies are mixed in terms of how effective it really is. Some studies have demonstrated positive effects on blood sugar levels, while others have not. How bitter melon works is open to speculation. Research suggests it may stimulate muscles to take in more glucose and maintain the function of insulin-producing beta-cells located in the pancreas.
Licorice Root (Glycyrrhiza glabra) 50 mg
Various animal studies reveal licorice exerts favorable effects on blood sugar and cholesterol levels, making it attractive to some who have metabolic syndrome (pre-diabetes). In one review of previously published human research, licorice appeared to reduce body weight by about 1 pound modestly. Weight loss should impact blood sugar in a positive way. At least one pre-clinical study appears to show that an extract of licorice (glabridin) improves memory in laboratory animals. Licorice might work by adjusting how the microbiome functions.
Cinnamon Bark Extract (Cinnamomum cassia) 50 mg
Cinnamon is well known to have blood sugar-lowering effects. Cassia cinnamon is the most common type of this spice and is the kind found in Diverxin SugaREX. When researchers analyzed 10 previous investigations, they reported cinnamon effectively and significantly reduced blood sugar, cholesterol, bad (LDL) cholesterol and triglycerides.
Researchers tend to use a spectrum of dosages ranging from about 100 mg to 6000 mg per day. This broad range may be the reason for the conflicting results when researchers attempt to see if it helps people with diabetes. Some studies reveal the spice lowers blood sugar and even HbA1c levels, while other investigations show no such effect.
Cinnamon is sometimes criticized because it contains a potentially toxic substance called coumarin. Since this Diverxin supplement is NSF-certified, this should mean it is coumarin-free.
Gymnema Sylvestre 50 mg
Gymnema Sylvestre is a shrub-like plant that grows in India and Asia and has been thought to be a therapeutic herb for thousands of years. It is still listed in the Indian Pharmacopoeia for its anti-diabetes effects. So what does modern science say? A review of 10 previous studies involving over 400 people concluded that Gymnema Sylvestre reduces fasting blood sugar, post-prandial blood sugar, and HbA1c levels after several months of use.
So how does it work? While some point to gymnemic acid, a substance found in the leaves, as the key blood sugar-lowering substance, it's probably more complicated than that. This may be why SugaREX contains whole-leaf Gymnema Sylvestre powder. When researchers gave people with diabetes either Gymnema Sylvestre or a placebo for 30 days, they observed not only lower blood sugar levels but also reduced cholesterol, triglyceride, and bad (LDL) cholesterol levels too.
Yarrow Flowers (Achillea millefolium) 50 mg
Also known as green arrow, Thousandleaf, and bloodwort, yarrow has been used since the time of the Druids. Despite this, however, little human research has been conducted to know for sure if it lowers blood sugar levels. Many people who suffer from diabetes also deal with fatty liver disease (NAFLD). In animals, yarrow has been shown to protect the liver from the harmful effects of a high-fat diet. The plant does appear to have anti-inflammatory and antioxidant benefits as well.
Cayenne Pepper (Capsicum annuum) 10 mg / 40M HU/G
Red pepper, also known as cayenne pepper, contains an extract called capsaicin, which not only is of interest for reducing arthritis pain and weight loss but also blood sugar issues. Capsaicin is one of the capsaicinoids, molecules thought to be at the heart of cayenne's health effects. Capsaicin is the substance that makes red peppers taste hot.
Various studies have demonstrated cayenne pepper appears to:
- Reduce post-prandial blood sugar levels
- Reduce ghrelin (which may reduce appetite)
- Increase glucose absorption by cells
- Increase GLP1 (which increases insulin secretion)
- Reduce cholesterol
The potency of the cayenne pepper used in SugaREX is 40M HU/G. If you're unfamiliar with this, it means 40 thousand heat units per gram. Heat units are also Scoville Heat Units, after Wilber Scoville, who 1912 created a method to classify how hot a food/spice was. Cayenne pepper has about 50,000 heat units so the type used in SugaREX is in that ballpark range.
Juniper Berry (Juniperus communis) 25 mg
Juniper trees are small evergreen trees whose berries are considered to have health-promoting effects. Like all berries, juniper berries contain a wide array of bioactive phytonutrients ranging from terpenes and carotenoids to tannins and anthocyanins. When juniper berries are given to animals, they lower blood sugar within a matter of weeks.
White Mulberry (Morus alba) 25 mg
Tales of white mulberry to treat illness date back over 1500 years. While in folk medicine, mulberries have been used to help the body heal from everything from fevers to poor eyesight, one thing people use it for today is to better blood sugar levels. So is there any proof?
In one study, white mulberry dropped post-prandial blood sugar by 16% when it was given to people with type II diabetes for three months. Equally intriguing is that HbA1c levels also declined too. In another three month long investigation, white mulberry reduced insulin levels and raised HDL levels compared to diabetic individuals taking a placebo. A review of 10 previous studies, concluded that white mulberries probably lowered insulin and blood sugar levels, although more rigorous studies should be conducted to know for sure.
Vanadium 200 mcg
Vanadium is a trace mineral and an element found on the periodic table of elements (atomic number 23). While human and animal investigations have demonstrated vanadium reduces blood sugar levels, the dosages needed are thought to be quite high. For example, in one investigation, 150 and 300 mg were used to achieve declines in glucose levels. The SugaREX Diverxin supplement has 200 micrograms of vanadium. This may be a good thing because animal research suggests high dosages of vanadium may be harmful to the kidneys.
Cordyceps & Kidney Function
Alpha lipoic acid 30 mg
Alpha lipoic acid is a popular supplement that's sometimes used because of its antioxidant effects. It turns out that some research suggests alpha lipoic acid may also benefit those with diabetes too. Some studies reveal alpha lipoic acid may help reduce diabetic neuropathy symptoms. Other studies have shown reductions in blood sugar too, although this is a bit controversial because not all studies show it affects glucose levels. The amounts used in research tend to be higher than that found in the SugaREX supplement.
L-Taurine 25 mg
Taurine is an amino acid that is often found in energy drinks, possibly due to some research finding it may improve mental focus. As for diabetes control, some researchers find lower taurine levels in those who have diabetes. However, this doesn't necessarily mean lack of taurine contributes to diabetes. In a review of 5 previous studies, it was concluded taurine could reduce fasting blood sugar levels, insulin resistance, and HbA1c. If it works, it may depend on the amount used and how far along one's diabetes is.
Taurine & Blood Pressure
What Countries Do The Ingredients Come From?
The company states this supplement is manufactured in the United States. Do the ingredients in SugaREX also come from the United States? The company does not say either way. Unfortunately, many supplement ingredients these days are sourced from other countries, including China.
Is SugarRX Organic?
The website for this supplement states that it is the “organic way” to support healthy blood sugar levels. The website also states that it is USA Organic too. USA Organic certification is seen as the best organic certification to have.
How Much Does Deverxin SugaREX Cost?
There are several purchase options. Here is what was seen when the site was visited:
- 1 bottle: $57 + $9.95 shipping = $66.95
- 2 bottles: $102.60 +$9.95 shipping = $112.55
- 4 bottles: $193.80 (free shipping)
- 6 bottles: $256.50 (free shipping)
- 12 bottles (1 year supply): $41.40 (free shipping)
When ordering, you also have the opportunity of joining the SugaREX Privileged Customer Club which provides you with a 40% discount ($22.80 savings) on all future shipments. Shipping is in addition to this amount. You will also be entered into their auto-ship program. This means you will regularly get bottles of SugaREX sent to your home at the discounted price of $44.15.
Check the official website for discounts, coupons, and updated price information.
What Countries Is Deverxin SugaREX Shipped To?
The Diverxin company, which is based in the US, also sends supplements to the UK, Australia, and New Zealand and also most European and Asian countries as well.
Diverxin Supplement Customer Reviews
The supplement doesn't seem to have been out long enough to garner many online testimonials from customers or before and after pictures. This will eventually change as more people try the supplement. If you try it yourself, see below to determine if SugaREX works for you.
Who Makes Diverxin SugaREX? Company Information
The company is called SugaREX. Another name is Diverxin, also known as Red Shopping Venture Inc. The company address is 1142 S. Diamond Bar Blvd # 191 Diamond Bar, CA 91765.
The address corresponds to the Diamond Bar Towncenter Mall which houses several businesses such as Walmart, Crunch Fitness, and a UPS Store. Another company that shares this address is Lumandar USA Inc. Another company name may be Detoxfix.com.
Red Venture Shopping LLC is unrelated to Red Ventures LLC, the digital media company behind websites such as Healthline, Healthgrades, Medical News Daily, and others.
The company produces a variety of other dietary supplements such as:
- Diverxin Cholesterol Reduction Pro
- Maximum Detoxify
- Femm Vigor
- Brain Vigor
- ProstaMaxx 7
Diverxin SugaREX Customer Service
The company offers email support email@example.com and on the website, you can also reach out to them using WhatsApp too. If you choose that option, you will have to install WhatsApp if you don't already have it. In a test of the company's responsiveness to customer questions, emailing support was disappointing with no answer after 72 hrs.
Diverxin customer service can be reached at 800-935-1381.
What Is ClickBank?
Clickbank is an online retail company that facilitates payments and checkout of supplements and other items to you. Many companies use Clickbank to make their business operations easier. Based in Boise, Idaho, Clickbank is a respected organization that has been in business since 1998 and has an A+ rating with the Better Business Bureau.
Where Is SugaREX Made?
While the manufacturing plant's location is not listed, it may be located in California since that is where the company is based. On the plus side, Diverxin SugaREX is made in an FDA and NSF-approved facility. NSF is an independent supplement certification program. The NSF program ensures the supplement:
- contains the ingredients and amounts stated on the label
- has no undeclared ingredients like steroids or drugs
- is free from toxins
The NSF performs its own testing on supplements to ensure accuracy.
How Long Until Diverxin SugaREX Works?
Blood sugar levels fluctuate throughout the day, so if it's working for you, you should see results within a few weeks. However, it will take a few months to see the hemoglobin A1C (HbA1c) decline. One bottle will not result in lower HbA1c levels. If you follow the company's use directions, it may take at least 3 to 4 bottles to see a reduction in HbA1c.
Diverxin SugaREX vs. The Competition
The SugaREX formula has not been compared to other supplements such as berberine, chromium, or cinnamon to see how well it stacks up. Here are a few similar popular dietary supplement reviews worth looking at:
How To Know if Diverxin SugaREX Is Really Working?
The easiest way is to monitor your blood sugar. This can be as easy as a finger stick with a glucose monitor you use at home. If you use a continuous glucose monitor (CGM) this should also give you an indication as well. If Sugar EX really works, you should start seeing results in a few weeks.
As for the other claims the company makes – boosting energy levels, improving leptin levels, etc. – that will be more difficult to pin down.
Does Diverxin SugaREX Have Side Effects: Who Should Talk To Their Doctor Before Taking?
No negative customer adverse reactions were known to occur when this review was created. That's good and to keep this trend going and minimize potential side effects you may experience, here are some things to consider:
- Start with less than is recommended for the first week. If there are side effects for you, taking less should help minimize them.
- Guggle may not be appropriate during pregnancy
- Don't use it if you are under the age of 18
- Stop taking SugaREX at least two weeks before surgery. Some ingredients may thin the blood.
- Speak to your doctor if you take blood thinner medications. Show your doctor the ingredients.
- In unhealthy people, licorice might reduce potassium levels and raise blood pressure
- Several ingredients in the supplement appear to lower blood sugar levels. Does this mean they might interact with diabetes medications and lower blood sugar too much? Ask your doctor and pharmacist.
- If you take any medications, show the ingredients to your doctor and pharmacist.
Diverxin SugaREX Pros & Cons
These are my personal opinions. Yours may be different.
|Ingredients make sense||No clinical research on SugarEX itself|
|Take just two capsules per day||Expensive|
|NSF certified||Bold claims|
|No proprietary blends||Slow email customer service replies|
|Vague return instructions|
Does Diverxin SugaREX Really Work?
While the ingredients make sense for a blood sugar support supplement, I'd like to see a few studies n the supplement. While SugaREX does not contain traditional ingredients like chromium picolinate or berberine, other ingredients in the formula do have their share of proof. Did SugaREX work for you?