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Is The Cholesterol Drug Repatha Safe?

By Joe 9 Comments

Repatha (evolocumab)  is a popular cholesterol-lowering medication. It's not a statin and must be injected. It's proven to dramatically reduce bad LDL cholesterol but several people have reported intense muscle pains occurring soon after taking the drug. In this interview, I sit down with Robert, a physician and marathon runner who describes what happened to him after he took the Repatha drug. He also talks about how long the drug stays in the body which is important if you are taking the medication and now and having similar side effects. This is episode 120 of the Joe Cannon Health podcast, available here and you can follow for free on Apple and Google Podcasts, Amazon Music, Spotify, Pandora, Alexa Echo, Radio Public, Gaana, and pretty much everywhere else.

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Repatha Video Podcast

Does Repatha Cause Muscle Pain (read the comments)

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Joe Cannon holds an MS in exercise science and a BS degree in chemistry and biology. He's the author of several books, been quoted in the New York Times, Shape Magazine, and The Daily Beast. Joe wrote the first book about exercise-induced rhabdomyolysis. He's been teaching about preventing rhabdo for over 10 years. He trains personal trainers, speaking to thousands each year, and has even lectured to the NASA community. Since the 1990s he's been investigating and teaching about dietary supplements. His website SupplementClarity.com is devoted to honest dietary supplement reviews.

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Comments

  1. jane says

    March 4, 2024 at 9:17 am

    I would like to just mention that I did not take Repatha but two shots of Leqvio and I would like to
    let you all know that if I had my druthers and could go back I would never ever get it…for what it has done to me

    Reply
    • Joe says

      March 5, 2024 at 12:08 pm

      Thank you for sharing Jane.

      Reply
  2. Martha Gray says

    May 28, 2023 at 2:54 pm

    Had 3 shot and was haveing muscle pain after the shot. i would have bad pain down the side of my leg at night it would be so bad it would wake me up,I have been off it for 2 months now and haveing muscle pain in my legs all the time and they feel weak.

    Reply
    • Joe says

      May 30, 2023 at 4:22 pm

      Martha, terribly sorry to learn about your pain. I have to feel that eventually it will get better. Have you spoken to your doctor about this pain?

      Reply
  3. Dede says

    January 19, 2022 at 1:49 pm

    Hi Joe,
    I had Bypass a year ago and was put on statins, could not tolerate because of painful side effects..went on Repatha, one injection a month. After 4 months I feel like I’m dying. My joints hurt so bad and my muscles ache all the time. I can’t remember anything anymore. My feet and hands burn and I have shortness of breath. I just feel like I’m 90..and now fighting depression because I don’t have the energy to go to the gym, walk or even get out of bed..The pain zaps my energy bad!!!
    I hope the damage is not permanent.

    My Cardiologist took me off and said to take Bergamot and Red Yeast Rice extract. He said for some people Repatha can cause neuropathy and dementia that are irreversible. I have stopped and it’s been about 3 weeks since last injection. No changes yet but I’m hopeful it will turn around and I can have my life back.

    I will do anything to feel normal at this point. I now have PTSD and have to see a therapist from the trauma of the Open heart surgery with all tons of complications I had, to dealing with the nasty side effects from all the drugs I’ve been on. I wouldn’t wish this on my worst enemy..any of it!

    Thanks for your webpage. Helps to know I’m not alone.

    Reply
    • Joe says

      January 19, 2022 at 6:33 pm

      Dede, oh I am so very sorry to hear about what you are dealing with. I cannot imagine. I was not aware of Repatha being connected to dementia. Thanks for the heads up on this. In case you missed it, here is my written Repatha reveiew. If you scroll to the bottom, you’ll see several other people have commented about their negative experiences with repatha
      Does Repatha Cause Muscle Pain?

      Red Yeast rice contains a naturally occuring statin substance. That’s why it works. Bergamont, which comes from the bergamot orange also has several studies showing it may reduce cholesterol levels. Here is my review of Bergamot and cholesterol research. Look through the comments in that review also.

      You are not alone Dede. I hope some of this is of help to you and your health and wellness continue to improve.

      Reply
      • Dede says

        January 19, 2022 at 7:37 pm

        keep up the good work shinning the light on the truth about statins and their sidekicks! They may not all feel the effects now but someday they will…when it’s to late.
        Thanks Joe

        Reply
        • Joe says

          January 20, 2022 at 10:47 am

          Thanks Dede 🙂

          Reply
    • Becci Lammi says

      March 16, 2022 at 4:03 pm

      Hi Dede,

      I empathize with you. I too had bypass surgery last year. Repatha is not a wonder drug for me! I posted my story on another thread and now I can’t find it. But I want you to know that you are not alone. I share your symptoms. I wish my doctor was as up to date and proactive as yours. I did not know that I could have permanent neuropathy and dementia. Thanks for sharing.

      Reply

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About

I'm Joe Cannon. I hold an MS in exercise science and a BS in chemistry and biology.

I've been quoted in the New York Times and Daily Beast to name a few. I've even lectured to the NASA community.

I'm the author of the first book on rhabdomyolysis (rhabdo) & exercise. I've conducted over 1,000 fitness certification classes.

Learn more about me

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Joe Cannon, MS has written for several publications including The Journal of Strength and Conditioning, Today's Dietitian, and Prevention. He's been quoted in the New York Times, lectured to NASA and has been a content consultant for Dateline NBC. He's the author of the first book ever published on rhabdomyolysis and exercise. Joe Cannon, has a BS in Chemistry and Biology and a MS in Exercise Science. He is a Certified Strength and Conditioning Specialist (CSCS) and a personal trainer certified by the National Strength and Conditioning Association (NSCA).
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